Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18025413 | 1.00 | POLB (0.37) | POLBTDP1CTDSP1APEX1 | |
| SCHEMBL13677572 | 1.00 | POLB (0.37) | POLBTDP1CTDSP1APEX1 | |
| SCHEMBL13040844 | 1.00 | POLB (0.37) | POLBTDP1CTDSP1APEX1 | |
| SCHEMBL638769 | 0.84 | POLB (0.46) | POLBTDP1CTDSP1APEX1 | |
| SCHEMBL1782951 | 0.81 | POLB (0.31) | POLBTDP1APEX1 | |
| SCHEMBL15800300 | 0.79 | EPHX1 (0.35) | — | |
| SCHEMBL24471633 | 0.78 | — | — | |
| SCHEMBL13924878 | 0.78 | — | — | |
| SCHEMBL25600270 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL12492014 | 0.74 | POLB (0.42) | POLBTDP1CTDSP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389699-B2 | Nucleic acid terminators incorporating a cationic moiety and methods for their use | APPLIED BIOSYSTEMS, LLC (US) | 2013-03-05 | — | — | US | disclosed |