Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2538072 | 0.89 | MET (0.53) | METKDR | |
| SCHEMBL12252040 | 0.87 | MET (0.61) | METKDR | |
| SCHEMBL12250886 | 0.87 | MET (0.62) | METKDR | |
| SCHEMBL2539129 | 0.86 | MET (0.51) | METKDR | |
| SCHEMBL13691198 | 0.85 | MET (0.57) | METKDR | |
| SCHEMBL12252283 | 0.83 | MET (0.69) | METKDR | |
| SCHEMBL12285925 | 0.83 | MET (0.71) | METKDR | |
| SCHEMBL2532431 | 0.83 | MET (0.65) | METKDR | |
| SCHEMBL2539374 | 0.83 | MET (0.59) | METKDR | |
| SCHEMBL12252284 | 0.83 | MET (0.70) | METKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455484-B2 | Selected inhibitors of protein tyrosine kinase activity | METHYLGENE INC. (CA) | 2013-06-04 | — | — | US | disclosed |
| US-8389541-B2 | Inhibitors of protein tyrosine kinase activity | METHYLGENE INC. (CA) | 2013-03-05 | — | — | US | disclosed |