Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.54 |
| ▸ | CA7 | P43166 | 3/20 | 0.54 |
| ▸ | XDH | P47989 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11888448 | 0.84 | MAPT (0.50) | SMN1; SMN2CYP1A2CYP2C19TSHRHPGD | |
| SCHEMBL8918126 | 0.81 | CA12 (0.65) | CA12CA1CA2CA9CA14 | |
| SCHEMBL14747746 | 0.81 | CA12 (0.56) | CA12CA1CA2CA9CA14 | |
| SCHEMBL28382770 | 0.78 | LMNA (0.54) | CA12CA1CA2CA9CA14 | |
| SCHEMBL31498198 | 0.75 | CA12 (0.56) | CA12CA1CA2CA9CA14 | |
| SCHEMBL10606130 | 0.74 | CA1 (0.68) | CA12CA1CA2CA9CA14 | |
| SCHEMBL9558381 | 0.73 | KDM4E (0.51) | CA12CA1CA2CA9CA14 | |
| Water SCHEMBL10398682 | 0.73 | CA1 (0.66) | CA12CA1CA2CA9CA14 | |
| SCHEMBL2913645 | 0.73 | KDM4E (0.53) | CA12CA1CA2CA9CA14 | |
| SCHEMBL8230251 | 0.73 | CA1 (0.67) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389564-B2 | Proteasome inhibitors | TRIPHASE RESEARCH AND DEVELOPMENT I CORP. (CA) | 2013-03-05 | — | — | US | disclosed |