Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 8/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26035353 | 0.88 | USP7 (0.58) | USP7ALDH1A1GRIN2BPOLBSMN1; SMN2 | |
| SCHEMBL20856977 | 0.88 | USP7 (0.73) | USP7ACHEALDH1A1GRIN2BPOLB | |
| SCHEMBL30063832 | 0.88 | USP7 (0.73) | USP7ACHEALDH1A1GRIN2BPOLB | |
| SCHEMBL14747842 | 0.86 | ALDH1A1 (0.56) | USP7ALDH1A1TDP1NPSR1POLB | |
| SCHEMBL14747838 | 0.84 | USP7 (0.53) | USP7ACHEALDH1A1GRIN2BTDP1 | |
| SCHEMBL14735333 | 0.82 | USP7 (0.79) | USP7 | |
| SCHEMBL14747849 | 0.82 | USP7 (0.64) | USP7ALDH1A1TDP1NPSR1GLA | |
| SCHEMBL14747839 | 0.82 | USP7 (0.48) | USP7ACHEALDH1A1TDP1NPSR1 | |
| SCHEMBL14747843 | 0.82 | USP7 (0.64) | USP7ALDH1A1TDP1NPSR1POLB | |
| SCHEMBL14747844 | 0.82 | USP7 (0.64) | USP7ALDH1A1TDP1NPSR1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565186-A1 | Selective and reversible inhibitors of ubiquitin specific protease 7 | Hybrigenics S.A. (FR) | 2013-03-06 | — | — | EP | disclosed |