Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 8/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4273522 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2SYKFFAR4ARKIF11 | |
| SCHEMBL184870 | 0.77 | SMN1; SMN2 (0.66) | SMN1; SMN2SYKFFAR4ARTP53 | |
| SCHEMBL84053 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2SYKFFAR4ARKIF11 | |
| SCHEMBL10030392 | 0.76 | GLA (0.54) | SMN1; SMN2SYKFFAR4ARKIF11 | |
| SCHEMBL80373 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2SYKFFAR4ARKIF11 | |
| SCHEMBL168982 | 0.74 | MPL (0.44) | SMN1; SMN2SYKARCYP11B1CYP11B2 | |
| SCHEMBL12859720 | 0.73 | SMN1; SMN2 (0.41) | SMN1; SMN2SYKFFAR4ARKIF11 | |
| SCHEMBL6371416 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2SYKFFAR4ARKIF11 | |
| SCHEMBL12773798 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2SYKFFAR4ARKIF11 | |
| SCHEMBL19267570 | 0.73 | SMN1; SMN2 (0.41) | SMN1; SMN2SYKFFAR4ARKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197857-B1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2013-03-06 | — | — | EP | disclosed |