Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 20/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1813067 | 0.92 | SLC6A9 (0.68) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL3072470 | 0.87 | SLC6A9 (0.57) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL3078411 | 0.84 | SLC6A9 (0.74) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL3077428 | 0.84 | SLC6A9 (0.74) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL3077440 | 0.80 | SLC6A9 (0.62) | SLC6A9KCNH2 | |
| SCHEMBL1813164 | 0.80 | SLC6A9 (0.65) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL14683684 | 0.80 | SLC6A9 (0.65) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL8229318 | 0.80 | SLC6A9 (0.65) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL14683682 | 0.80 | SLC6A9 (0.65) | SLC6A9KCNH2SLC6A5 | |
| SCHEMBL14683711 | 0.79 | SLC6A9 (0.64) | SLC6A9KCNH2SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035371-B1 | SUBSTITUTED PHENYL METHANONE DERIVATIVES AND THEIR USE AS GLYT1 AND GLYT2 RECEPTOR INHIBITORS | HOFFMANN LA ROCHE (CH) | 2013-03-06 | — | — | EP | disclosed |