Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 4/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.37 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PNLIP | P16233 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14748410 | 0.83 | ALDH1A1 (0.54) | ARCA1CA2TSHRALDH1A1 | |
| SCHEMBL5801556 | 0.82 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL8004927 | 0.80 | PDE4B (0.56) | ARPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8006259 | 0.79 | TTR (0.57) | PDE4APDE4BPDE4CPDE4DTTR | |
| SCHEMBL19622266 | 0.77 | ALDH1A1 (0.47) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL8007094 | 0.77 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19622181 | 0.75 | AR (0.42) | ARPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8007552 | 0.74 | PDE4A (0.50) | ARPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14748434 | 0.74 | PDE4A (0.50) | ARPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14748450 | 0.74 | PDE4B (0.44) | ARPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2564857-A1 | Boron-containing small molecules as anti-inflammatory agents | Anacor Pharmaceuticals, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |