Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14728253 | 0.78 | MAPT (0.56) | MAPTSMN1; SMN2NPSR1ALDH1A1KMT2A | |
| SCHEMBL14716115 | 0.76 | PDE4B (0.59) | MAPTSMN1; SMN2NPSR1ALDH1A1KMT2A | |
| SCHEMBL14728254 | 0.72 | MAPT (0.52) | MAPTSMN1; SMN2NPSR1ALDH1A1KMT2A | |
| SCHEMBL14728264 | 0.71 | PDE4B (0.53) | MAPTSMN1; SMN2NPSR1ALDH1A1KMT2A | |
| SCHEMBL14748488 | 0.71 | MAPT (0.34) | MAPTSMN1; SMN2NPSR1ALDH1A1KMT2A | |
| SCHEMBL14716159 | 0.61 | KDM4E (0.65) | MAPTSMN1; SMN2NPSR1ALDH1A1KMT2A | |
| SCHEMBL30630102 | 0.61 | KDM4E (0.62) | MAPTSMN1; SMN2NPSR1ALDH1A1KMT2A | |
| SCHEMBL19786607 | 0.61 | TYMS (0.60) | MAPTSMN1; SMN2NPSR1ALDH1A1KMT2A | |
| SCHEMBL14728517 | 0.60 | NPSR1 (0.58) | NPSR1ALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL14716459 | 0.59 | KDM4E (0.44) | MAPTNPSR1ALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565194-A1 | IMIDAZO[1,2-a]PYRIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2013-03-06 | — | — | EP | disclosed |