Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | CASP1 | P29466 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | CASP7 | P55210 | 5/20 | 0.58 |
| ▸ | GLA | P06280 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14716159 | 0.97 | KDM4E (0.65) | KDM4EKMT2ANPSR1MEN1CYP1A2 | |
| SCHEMBL14716146 | 0.84 | KDM4E (0.51) | KDM4EKMT2ANPSR1MEN1CYP1A2 | |
| SCHEMBL14728254 | 0.82 | MAPT (0.52) | KDM4EKMT2ANPSR1MEN1CYP1A2 | |
| SCHEMBL14728253 | 0.81 | MAPT (0.56) | KDM4EKMT2ANPSR1MEN1CYP1A2 | |
| SCHEMBL26702811 | 0.81 | KDM4E (0.80) | KDM4EKMT2ANPSR1MEN1CYP1A2 | |
| SCHEMBL26703074 | 0.80 | KDM4E (0.75) | KDM4EKMT2ANPSR1MEN1CYP1A2 | |
| SCHEMBL26608114 | 0.79 | KDM4E (0.95) | KDM4EKMT2ANPSR1MEN1CYP1A2 | |
| SCHEMBL26703076 | 0.79 | KDM4E (0.74) | KDM4EKMT2ANPSR1MEN1CYP1A2 | |
| SCHEMBL14728219 | 0.78 | MAPK1 (0.77) | KDM4EKMT2ANPSR1MEN1CYP1A2 | |
| SCHEMBL26702990 | 0.77 | KDM4E (0.82) | KDM4EKMT2ANPSR1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624031-B2 | Inhibitors of ubiquitin specific peptidase 22 (USP22) and uses thereof for treating diseases and disorders | NORTHWESTERN UNIVERSITY (US) | 2026-05-12 | — | — | US | disclosed |
| US-20230339942-A1 | INHIBITORS OF UBIQUITIN SPECIFIC PEPTIDASE 22 (USP22) AND USES THEREOF FOR TREATING DISEASES AND DISORDERS | NORTHWESTERN UNIVERSITY | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12624031-B2 | Inhibitors of ubiquitin specific peptidase 22 (USP22) and uses thereof for treating diseases and disorders | USP2, USP19, USP24 | KDM4E 451/4885KMT2A 453/4885NPSR1 4407/4885 |
| US-20230339942-A1 | INHIBITORS OF UBIQUITIN SPECIFIC PEPTIDASE 22 (USP22) AND USES THEREOF FOR TREATING DISEASES AND DISORDERS | USP19, USP24, USP2 | KDM4E 1113/4885KMT2A 1263/4885NPSR1 4325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.