Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 5/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14728434 | 0.85 | KDM4E (0.54) | KDM4EPKMTSHRMAPK1CASP1 | |
| SCHEMBL14728421 | 0.75 | KDM4E (0.56) | KDM4EPKMTSHRMAPK1CASP1 | |
| SCHEMBL14728436 | 0.73 | KDM4E (0.55) | KDM4EPKMTSHRMAPK1CASP1 | |
| SCHEMBL14728419 | 0.73 | KDM4E (0.56) | KDM4EPKMTSHRMAPK1CASP1 | |
| SCHEMBL14748490 | 0.71 | MAPK1 (0.48) | KDM4EPKMTSHRMAPK1CASP1 | |
| SCHEMBL14728410 | 0.69 | KDM4E (0.58) | KDM4EPKMTSHRMAPK1CASP1 | |
| SCHEMBL14728418 | 0.69 | KDM4E (0.57) | KDM4EPKMTSHRMAPK1CASP1 | |
| SCHEMBL14728391 | 0.67 | KDM4E (0.51) | KDM4EPKMTSHRMAPK1CASP1 | |
| SCHEMBL14728402 | 0.66 | KDM4E (0.54) | KDM4EPKMTSHRMAPK1CASP1 | |
| SCHEMBL14728482 | 0.66 | KDM4E (0.51) | KDM4EPKMTSHRMAPK1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565194-A1 | IMIDAZO[1,2-a]PYRIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2013-03-06 | — | — | EP | disclosed |