Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 7/20 | 0.55 |
| ▸ | ATXN2 | Q99700 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25935199 | 0.89 | ENPP2 (0.58) | ENPP2ATXN2MEN1KMT2ANPSR1 | |
| SCHEMBL30121535 | 0.88 | ENPP2 (0.62) | ENPP2ATXN2MEN1KMT2ANPSR1 | |
| SCHEMBL14731552 | 0.88 | ENPP2 (0.59) | ENPP2ATXN2MEN1KMT2ANPSR1 | |
| SCHEMBL25376016 | 0.86 | ENPP2 (0.55) | ENPP2ATXN2MEN1KMT2ANPSR1 | |
| SCHEMBL10082704 | 0.85 | ENPP2 (0.58) | ENPP2ATXN2MEN1KMT2ANPSR1 | |
| SCHEMBL19633325 | 0.84 | ENPP2 (0.53) | ENPP2ATXN2MEN1KMT2ANPSR1 | |
| SCHEMBL1675680 | 0.83 | MEN1 (0.66) | MEN1KMT2ANPSR1SMN1; SMN2CYP2C19 | |
| SCHEMBL20669160 | 0.83 | ENPP2 (0.60) | ENPP2ATXN2MEN1KMT2ANPSR1 | |
| SCHEMBL30746332 | 0.82 | MEN1 (0.51) | ENPP2ATXN2MEN1KMT2ANPSR1 | |
| SCHEMBL7711512 | 0.82 | ENPP2 (0.54) | ENPP2ATXN2MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565194-A1 | IMIDAZO[1,2-a]PYRIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2013-03-06 | — | — | EP | disclosed |