⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6125510 | 0.64 | — | — | |
| SCHEMBL1927501 | 0.64 | — | — | |
| SCHEMBL1828282 | 0.62 | — | — | |
| SCHEMBL17186581 | 0.62 | — | — | |
| SCHEMBL333505 | 0.60 | — | — | |
| SCHEMBL17803267 | 0.58 | — | — | |
| SCHEMBL11097856 | 0.57 | — | — | |
| SCHEMBL458090 | 0.56 | — | — | |
| SCHEMBL849669 | 0.56 | — | — | |
| SCHEMBL7190504 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160280691-A1 | TRIAZOLE INTERMEDIATES USEFUL IN THE SYNTHESIS OF PROTECTED N-ALKYLTRIAZOLECARBALDEHYDES | BIOMARIN PHARMACEUTICAL INC. | 2016-09-29 | — | — | US | claimed |
| EP-3066084-A1 | TRIAZOLE INTERMEDIATES USEFUL IN THE SYNTHESIS OF PROTECTED N-ALKYLTRIAZOLECARBALDEHYDES | Medivation Technologies, Inc. (US) | 2016-09-14 | — | — | EP | claimed |
| CN-105916846-A | Triazole intermediates useful in the synthesis of protected N-alkyltriazolecarbaldehydes | 麦迪韦逊科技有限公司 | 2016-08-31 | — | — | CN | claimed |
| WO-2015069851-A1 | TRIAZOLE INTERMEDIATES USEFUL IN THE SYNTHESIS OF PROTECTED N-ALKYLTRIAZOLECARBALDEHYDES | BIOMARIN PHARMACEUTICAL INC. (US) | 2015-05-14 | — | — | WO | claimed |
| EP-0090366-A1 | 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-05 | — | — | EP | claimed |
| US-20160280691-A1 | TRIAZOLE INTERMEDIATES USEFUL IN THE SYNTHESIS OF PROTECTED N-ALKYLTRIAZOLECARBALDEHYDES | BIOMARIN PHARMACEUTICAL INC. | 2016-09-29 | — | — | US | disclosed |
| EP-3066084-A1 | TRIAZOLE INTERMEDIATES USEFUL IN THE SYNTHESIS OF PROTECTED N-ALKYLTRIAZOLECARBALDEHYDES | Medivation Technologies, Inc. (US) | 2016-09-14 | — | — | EP | disclosed |
| CN-105916846-A | Triazole intermediates useful in the synthesis of protected N-alkyltriazolecarbaldehydes | 麦迪韦逊科技有限公司 | 2016-08-31 | — | — | CN | disclosed |
| WO-2015069851-A1 | TRIAZOLE INTERMEDIATES USEFUL IN THE SYNTHESIS OF PROTECTED N-ALKYLTRIAZOLECARBALDEHYDES | BIOMARIN PHARMACEUTICAL INC. (US) | 2015-05-14 | — | — | WO | disclosed |
| US-7915241-B2 | Reacting a sulfone intermediate, possessing a (5E) or (5Z) configuration with an aldehyde having an (R) or an (S) configuration in the presence of a strong base, in an aprotic solvent; synthetic analog of vitamin D3-calcipotriol, biologically active compound used in medical treatment | INSTYTUT FARMACEUTYCZNY (PL) | 2011-03-29 | — | — | US | disclosed |
| US-20050119241-A1 | Preparation of 24 alkyl analogs of cholecalciferol and non-racemic compounds | INSTYTUT FARMACEUTYCZNY (PL) | 2005-06-02 | — | — | US | disclosed |
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| EP-0090366-A1 | 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-05 | — | — | EP | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4399135-A | ANTIBIOTICS | RHONE-POULENC INDUSTRIES (FR) | 1983-08-16 | — | — | US | disclosed |
| US-4399135-A | ANTIBIOTICS | RHONE-POULENC INDUSTRIES (FR) | 1983-08-16 | — | — | US | disclosed |
| US-4370478-A | Oxacephalosporins | RHONE-POULENC INDUSTRIES (FR) | 1983-01-25 | — | — | US | disclosed |
| US-4369315-A | ANTIBIOTIC | RHONE-POULENC INDUSTRIES (FR) | 1983-01-18 | — | — | US | disclosed |
| US-4369314-A | Oxacephalosporins | RHONE-POULENC INDUSTRIES (FR) | 1983-01-18 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |