SCHEMBL333505

SCHEMBL333505

C=CCn1[c]nnn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17186581 0.64
SCHEMBL7082937 0.60
SCHEMBL4591384 0.60
SCHEMBL1474875 0.60
SCHEMBL4214340 0.58
SCHEMBL299712 0.57
SCHEMBL7184246 0.56
SCHEMBL1140198 0.56
SCHEMBL14953658 0.56
SCHEMBL290880 0.53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 332 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3743430-B1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2023-08-02 EP claimed
US-11618753-B2 Aminopyrrolotriazines as kinase inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2023-04-04 US claimed
CN-113173917-A 1-alkyl-5-tetrazolyl/pyrimidone-1H-indole-3-carbonitrile compound and preparation method and application thereof 沈阳药科大学 2021-07-27 CN claimed
EP-3743430-A1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS Bristol-Myers Squibb Company (US) 2020-12-02 EP claimed
US-20200347071-A1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2020-11-05 US claimed
WO-2019147782-A1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2019-08-01 WO claimed
EP-3177287-A1 ANTIDIABETIC BICYCLIC COMPOUNDS Merck Sharp & Dohme Corp. (US) 2017-06-14 EP claimed
US-20160326125-A1 SULFONE AMIDE LINKED BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE BRISTOL MYERS SQUIBB CO (US) 2016-11-10 US claimed
WO-2016022742-A1 ANTIDIABETIC BICYCLIC COMPOUNDS MERCK SHARP & DOHME CORP. (US) 2016-02-11 WO claimed
EP-1848435-B1 COMPOUNDS AGAINST INFLAMMATIONS AND IMMUNE-RELATED USES SYNTA PHARMACEUTICALS CORP (US) 2016-01-20 EP claimed
US-4385181-A CHAMICAL INTERMEDIATES FOR CEPHALOSPORINS RHONE POULENC INDUSTRIES (FR) 1983-05-24 US claimed
EP-0068466-A1 4-Aryl or heteroaryl thio-2-oxo-1-azetidinesulfonic acid salts and process for their preparation E.R. Squibb &amp; Sons, Inc. (US) 1983-01-05 EP claimed
US-4364944-A BACTERICIDAL ANTIBIOTICS DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-12-21 US claimed
US-4362725-A ANTIBIOTICS DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-12-07 US claimed
EP-0054677-A2 Cephalosporins, process for their preparation and pharmaceutical compositions containing them Dr. Karl Thomae GmbH (DE) 1982-06-30 EP claimed
US-4304770-A Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-12-08 US claimed
US-4165429-A 7α-METHOXY-CEPHALOSPORANIC ACID DERIVATIVES YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1979-08-21 US claimed
US-4103015-A TRICYCLIC THIOXANTHONE-10,10-DIOXIDES BURROUGHS WELLCOME CO. (US) 1978-07-25 US claimed
US-3978050-A BACTERICIDES E. R. SQUIBB & SONS, INC. (US) 1976-08-31 US claimed
US-3950330-A BACTERICIDES E. R. SQUIBB & SONS, INC. (US) 1976-04-13 US claimed