Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CLK2 | P49760 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TOP1 | P11387 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30388535 | 0.93 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL14749181 | 0.93 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL680655 | 0.93 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL14208173 | 0.91 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL680312 | 0.87 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL28577329 | 0.85 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL28564185 | 0.85 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL28564184 | 0.85 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL28577331 | 0.85 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL28563156 | 0.85 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2551268-B1 | Process for the preparation of moxifloxacin hydrochloride and intermediates thereof | FIS FABBRICA ITALIANA SINTETICI SPA (IT) | 2017-01-18 | — | — | EP | disclosed |
| US-8975408-B2 | Moxifloxacin hydrochloride compounds and intermediates and methods for making same | F.I.S.—Fabbrica Italiana Sintetici S.p.A. (IT) | 2015-03-10 | — | — | US | disclosed |
| US-8975408-B2 | Moxifloxacin hydrochloride compounds and intermediates and methods for making same | F.I.S.—Fabbrica Italiana Sintetici S.p.A. (IT) | 2015-03-10 | — | — | US | disclosed |
| US-20140135501-A1 | MOXIFLOXACIN HYDROCHLORIDE COMPOUNDS AND INTERMEDIATES AND METHODS FOR MAKING SAME | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2014-05-15 | — | — | US | disclosed |
| US-20140135501-A1 | MOXIFLOXACIN HYDROCHLORIDE COMPOUNDS AND INTERMEDIATES AND METHODS FOR MAKING SAME | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2014-05-15 | — | — | US | disclosed |
| US-8664398-B2 | Moxifloxacin hydrochloride compounds and intermediates and methods for making same | F.I.S.—Fabbrica Italiana Sintetici S.p.A. (IT) | 2014-03-04 | — | — | US | disclosed |
| US-8664398-B2 | Moxifloxacin hydrochloride compounds and intermediates and methods for making same | F.I.S.—Fabbrica Italiana Sintetici S.p.A. (IT) | 2014-03-04 | — | — | US | disclosed |
| US-20130059880-A1 | MOXIFLOXACIN HYDROCHLORIDE COMPOUNDS AND INTERMEDIATES AND METHODS FOR MAKING SAME | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2013-03-07 | — | — | US | disclosed |
| US-20130059880-A1 | MOXIFLOXACIN HYDROCHLORIDE COMPOUNDS AND INTERMEDIATES AND METHODS FOR MAKING SAME | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135501-A1 | MOXIFLOXACIN HYDROCHLORIDE COMPOUNDS AND INTERMEDIATES AND METHODS FOR MAKING SAME | CYP3A7, CYP2C9, CYP3A5 | KDM4E 3341/4885ALDH1A1 1626/4885HPGD 394/4885 |
| US-20130059880-A1 | MOXIFLOXACIN HYDROCHLORIDE COMPOUNDS AND INTERMEDIATES AND METHODS FOR MAKING SAME | CYP3A7, CYP2C9, CYP3A5 | KDM4E 3341/4885ALDH1A1 1626/4885HPGD 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.