SCHEMBL14749236

SCHEMBL14749236

Cc1ccc(Cc2cnc(-c3nc4c(N(C)S(C)(=O)=O)cc(N5CCOCC5)cn4c(=O)c3O)[nH]2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34
PIK3CB P42338 3/20 0.33
PIK3CA P42336 3/20 0.33
PIK3CD O00329 2/20 0.33
SLC2A2 P11168 1/20 0.32
ATM Q13315 2/20 0.32
ALDH1A1 P00352 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SRPK1 Q96SB4 1/20 0.32
PAK1 Q13153 3/20 0.32
MAPT P10636 1/20 0.32
RECQL P46063 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
DGAT1 O75907 1/20 0.31
EPHB4 P54760 1/20 0.31
AXL P30530 1/20 0.31
GAA P10253 1/20 0.31
BRD4 O60885 1/20 0.31
AKT1 P31749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12881009 0.94 AKT1 (0.35) CNR1CNR2PIK3CASLC2A2ATM
Hydrochloric Acid SCHEMBL1221970 0.93 AKT1 (0.35) CNR1CNR2PIK3CASLC2A2ATM
SCHEMBL14749234 0.82 PIK3CD (0.33) CNR1CNR2PIK3CBPIK3CAPIK3CD
SCHEMBL12894316 0.82 PIK3CA (0.33) PIK3CAALDH1A1SRPK1PAK1RECQL
SCHEMBL13512867 0.81 SLC2A1 (0.34) PIK3CBPIK3CAPIK3CDATMMAPT
SCHEMBL14749235 0.81 BRD4 (0.32) CNR1CNR2PIK3CBPIK3CAPIK3CD
SCHEMBL1222478 0.81 USP2 (0.34) PIK3CBPIK3CAPIK3CDALDH1A1SRPK1
SCHEMBL12880832 0.78 ALDH1A1 (0.36) PIK3CBPIK3CAPIK3CDATMALDH1A1
Hydrochloric Acid SCHEMBL1221960 0.78 ALDH1A1 (0.36) PIK3CBPIK3CAPIK3CDALDH1A1MAPT
SCHEMBL1222176 0.76 CYP1A2 (0.35) PIK3CAALDH1A1MAPTRECQLAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130059865-A1 COMPOUNDS HAVING ANTIVIRAL PROPERTIES AVEXA LIMITED (AU) 2013-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130059865-A1 COMPOUNDS HAVING ANTIVIRAL PROPERTIES ZC3HAV1, ACE, EIF2AK2 CNR1 2425/4885CNR2 3533/4885PIK3CB 2323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.