SCHEMBL14749542

SCHEMBL14749542

CC1COC(c2cc(F)c(-c3cc(F)c(CF)c(F)c3)c(F)c2)OC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13614599 0.91
SCHEMBL15180939 0.85 CYP11B1 (0.31)
SCHEMBL13171680 0.83 CYP11B1 (0.33)
SCHEMBL880992 0.82
SCHEMBL13863718 0.82
SCHEMBL14235166 0.80
SCHEMBL13002705 0.80 CYP11B1 (0.33)
SCHEMBL15180942 0.79 CYP11B1 (0.34)
SCHEMBL13614788 0.79
SCHEMBL27322007 0.79 CYP11B1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9938464-B2 Liquid crystal medium and liquid crystal display MERCK PATENT GMBH (DE) 2018-04-10 US disclosed
US-9862887-B2 Liquid crystal medium and liquid crystal display MERCK PATENT GMBH (DE) 2018-01-09 US disclosed
US-9822305-B2 Liquid crystal medium and liquid crystal display MERCK PATENT GMBH (DE) 2017-11-21 US disclosed
US-20170226422-A1 POLYMERISABLE MESOGENIC COMPOUND, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2017-08-10 US disclosed
US-9612445-B2 Lens element MERCK PATENT GMBH (DE) 2017-04-04 US disclosed
US-20170002290-A1 ELECTRO-RHEOLOGICAL FLUID AND HAPTIC DEVICE MERCK PATENT GMBH (DE) 2017-01-05 US disclosed
US-20160326436-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2016-11-10 US disclosed
US-9475990-B2 Liquid crystal medium and liquid crystal display MERCK PATENT GMBH (DE) 2016-10-25 US disclosed
US-20150301344-A1 LENS ELEMENT MERCK PATENT GMBH (DE) 2015-10-22 US disclosed
US-20150247089-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2015-09-03 US disclosed
US-20150129800-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2015-05-14 US disclosed
US-20140225035-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2014-08-14 US disclosed
US-20140158934-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2014-06-12 US disclosed
US-8659737-B2 Liquid crystal medium and liquid crystal display MERCK PATENT GMBH (DE) 2014-02-25 US disclosed
US-20130057947-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-03-07 US disclosed