SCHEMBL14749604

COC[C@H]1CC[C@@H]2/C1=C\[C@]1(C)C(=C(C(C)C)C[C@@H]1O)[C@@H](O[C@H]1O[C@H](CO)C(O)C(O)C1O)[C@H](O)[C@@H]2C

nearest known ligand 0.57

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	YWHAZ	P63104	5/20	0.57

▸	RAF1	P04049	1/20	0.37

▸	YWHAH	Q04917	1/20	0.37

▸	PTPN1	P18031	2/20	0.35

▸	SYNJ2	O15056	2/20	0.34

▸	POLB	P06746	1/20	0.34

▸	STAT3	P40763	4/20	0.33

▸	PTPN7	P35236	1/20	0.33

▸	DUSP3	P51452	1/20	0.33

▸	IL2	P60568	1/20	0.33

▸	MAPT	P10636	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29608463	1.00	YWHAZ (0.57)	YWHAZRAF1YWHAHPTPN1SYNJ2
SCHEMBL14749605	0.93	YWHAZ (0.49)	YWHAZRAF1YWHAHPTPN1SYNJ2
SCHEMBL14749613	0.88	YWHAZ (0.73)	YWHAZRAF1YWHAH
SCHEMBL13770408	0.88	YWHAZ (0.73)	YWHAZRAF1YWHAH
SCHEMBL14749717	0.83	YWHAZ (0.74)	YWHAZRAF1YWHAH
SCHEMBL13764968	0.82	YWHAZ (0.81)	YWHAZPTPN1
SCHEMBL14749539	0.80	YWHAZ (0.65)	YWHAZRAF1YWHAHPTPN1SYNJ2
SCHEMBL29380328	0.80	YWHAZ (0.65)	YWHAZRAF1YWHAHPTPN1SYNJ2
SCHEMBL14749541	0.79	YWHAZ (0.90)	YWHAZ
SCHEMBL14749566	0.76	YWHAZ (0.89)	YWHAZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2013031975-A1	METHOD FOR PRODUCING INTERMEDIATE FOR BIOSYNTHESIS OF FUSICOCCIN A, AND SYNTHASE FOR USE IN SAID METHOD	DAIRI TOHRU (JP)	2013-03-07	—	—	WO	disclosed