Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.37 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730399 | 1.00 | OR51E2 (0.38) | OR51E2CRBNFKBP5TSHRTHRB | |
| SCHEMBL14749813 | 0.88 | CRBN (0.36) | OR51E2CRBNFKBP5TSHR | |
| SCHEMBL15215529 | 0.88 | CRBN (0.36) | OR51E2CRBNFKBP5TSHR | |
| SCHEMBL2603211 | 0.88 | CRBN (0.36) | OR51E2CRBNFKBP5TSHR | |
| SCHEMBL15719136 | 0.77 | OR51E2 (0.35) | OR51E2CRBNFKBP5 | |
| SCHEMBL14432979 | 0.77 | CRBN (0.35) | OR51E2CRBNFKBP5 | |
| SCHEMBL6155366 | 0.74 | — | — | |
| SCHEMBL14671531 | 0.74 | — | — | |
| SCHEMBL14749811 | 0.74 | — | — | |
| SCHEMBL7626928 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013031922-A1 | PYRAZOLE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | 日本たばこ産業株式会社 (JP) | 2013-03-07 | — | — | WO | disclosed |