SCHEMBL14756121

SCHEMBL14756121

CCn1c(C)cnc1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9951376 0.81 ALDH1A1 (0.37)
Iodide SCHEMBL28161167 0.79 ALDH1A1 (0.36)
Bromide SCHEMBL28286963 0.79 ALDH1A1 (0.36)
SCHEMBL28166287 0.78 MAPK1 (0.34)
SCHEMBL13274470 0.78 ALDH1A1 (0.46)
SCHEMBL1184137 0.76
SCHEMBL27527449 0.76
SCHEMBL13541809 0.76 CYP2C19 (0.33)
SCHEMBL10235421 0.76 MAPK1 (0.33)
SCHEMBL24336172 0.75 MAPK1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113939522-B Organosilane, ionic organosilane, film composition and film 3M创新有限公司 2024-12-17 CN disclosed
WO-2023076626-A1 RXFP1 AGONISTS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-05-04 WO disclosed
EP-3983418-A1 ORGANOSILANE, IONIC ORGANOSILANE, MEMBRANE COMPOSITION, AND MEMBRANE 3M Innovative Properties Company (US) 2022-04-20 EP disclosed
WO-2021064141-A1 INHIBITORS OF DUAL SPECIFICITY TYROSINE PHOSPHORYLATION REGULATED KINASE 1B TOLREMO THERAPEUTICS AG (CH) 2021-04-08 WO disclosed
US-9908853-B2 Inhibitors of peptidyl arginine deiminase (PAD) enzymes and uses thereof THE HOSPITAL FOR SICK CHILDREN (CA) 2018-03-06 US disclosed
US-20160023991-A1 PPAR AGONISTS SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2016-01-28 US disclosed
US-20140243286-A1 BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME COFERON, INC. (US) 2014-08-28 US disclosed
WO-2013033268-A2 BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME COFERON, INC. (US) 2013-03-07 WO disclosed
WO-2013033270-A2 BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME COFERON, INC. (US) 2013-03-07 WO disclosed
WO-2013033269-A1 BIOORTHOGONAL MONOMERS CAPABLE OF DIMERIZING AND TARGETING BROMODOMAINS AND METHODS OF USING SAME COFERON, INC. (US) 2013-03-07 WO disclosed