Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15984907 | 0.81 | KAT2B (0.97) | KAT2BSMN1; SMN2MAPTPKMPOLB | |
| SCHEMBL14756009 | 0.81 | KAT2B (0.69) | KAT2BSMN1; SMN2MAPTPKMPOLB | |
| Hydrochloric Acid SCHEMBL513299 | 0.80 | KAT2B (1.00) | KAT2BMAPTPKMPOLBHCAR3 | |
| SCHEMBL15984906 | 0.79 | KAT2B (0.74) | KAT2BSMN1; SMN2MAPTPKMPOLB | |
| SCHEMBL5983182 | 0.79 | KAT2B (0.69) | KAT2BSMN1; SMN2MAPTPKMPOLB | |
| SCHEMBL15984903 | 0.72 | KAT2B (0.79) | KAT2BSMN1; SMN2MAPTPKMPOLB | |
| SCHEMBL14756010 | 0.71 | KAT2B (0.70) | KAT2BSMN1; SMN2MAPTPKMPOLB | |
| SCHEMBL14754095 | 0.71 | KAT2B (0.59) | KAT2BSMN1; SMN2MAPTHCAR3ALDH1A1 | |
| SCHEMBL22456033 | 0.71 | KAT2B (0.61) | KAT2BSMN1; SMN2MAPTPKMHCAR3 | |
| SCHEMBL1957469 | 0.70 | SMN1; SMN2 (1.00) | KAT2BSMN1; SMN2MAPTPKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033268-A2 | BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |