Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 15/20 | 0.56 |
| ▸ | BRD2 | P25440 | 14/20 | 0.56 |
| ▸ | BRD3 | Q15059 | 14/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15980885 | 0.89 | BRD4 (0.69) | BRD4BRD2BRD3POLB | |
| SCHEMBL14756326 | 0.74 | BRD4 (0.74) | BRD4BRD2BRD3POLB | |
| SCHEMBL14756378 | 0.73 | BRD4 (0.76) | BRD4BRD2BRD3POLB | |
| SCHEMBL16771434 | 0.73 | BRD4 (0.69) | BRD4BRD2BRD3POLB | |
| SCHEMBL14756412 | 0.73 | BRD4 (0.79) | BRD4BRD2BRD3POLB | |
| SCHEMBL16758217 | 0.72 | BRD4 (1.00) | BRD4BRD2BRD3POLB | |
| SCHEMBL14756367 | 0.69 | BRD4 (0.71) | BRD4BRD2BRD3POLB | |
| SCHEMBL14757067 | 0.69 | BRD4 (0.67) | BRD4BRD2BRD3POLB | |
| SCHEMBL16771645 | 0.68 | BRD4 (0.70) | BRD4BRD2BRD3 | |
| SCHEMBL14756379 | 0.68 | BRD4 (0.70) | BRD4BRD2BRD3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033268-A2 | BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |