Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 15/20 | 0.69 |
| ▸ | BRD2 | P25440 | 15/20 | 0.69 |
| ▸ | BRD3 | Q15059 | 15/20 | 0.69 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.55 |
| ▸ | F13A1 | P00488 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | TGM1 | P22735 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15980885 | 0.82 | BRD4 (0.69) | BRD4BRD2BRD3POLB | |
| SCHEMBL16758237 | 0.81 | BRD4 (0.70) | BRD4BRD2BRD3POLB | |
| SCHEMBL14756412 | 0.80 | BRD4 (0.79) | BRD4BRD2BRD3POLB | |
| SCHEMBL16758217 | 0.79 | BRD4 (1.00) | BRD4BRD2BRD3POLB | |
| SCHEMBL10042200 | 0.79 | TDP1 (0.65) | F13A1TGM2TGM1POLB | |
| SCHEMBL14756378 | 0.79 | BRD4 (0.76) | BRD4BRD2BRD3POLB | |
| SCHEMBL14756367 | 0.78 | BRD4 (0.71) | BRD4BRD2BRD3POLB | |
| SCHEMBL14757067 | 0.78 | BRD4 (0.67) | BRD4BRD2BRD3POLB | |
| SCHEMBL14756326 | 0.78 | BRD4 (0.74) | BRD4BRD2BRD3POLB | |
| SCHEMBL14756379 | 0.77 | BRD4 (0.70) | BRD4BRD2BRD3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015081280-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION | COFERON, INC. (US) | 2015-06-04 | — | — | WO | disclosed |