Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.49 |
| ▸ | F13A1 | P00488 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15985340 | 0.83 | MAPT (0.46) | KDM4EMAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL15981456 | 0.79 | ADRB2 (0.39) | KDM4EMAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL19385987 | 0.78 | HTT (0.55) | ALDH1A1HPGDMTNR1AMTNR1BHTT | |
| SCHEMBL29858122 | 0.78 | HTT (0.55) | ALDH1A1HPGDMTNR1AMTNR1BHTT | |
| SCHEMBL14757171 | 0.77 | KDM4E (0.47) | KDM4EMAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL14757173 | 0.76 | KDM4E (0.49) | KDM4EMAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL14756946 | 0.75 | KDM4E (0.73) | KDM4EMAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL15981455 | 0.74 | RECQL (0.41) | KDM4EMAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL14757023 | 0.74 | KDM4E (0.54) | KDM4EMAPTHSD17B10ALDH1A1LMNA | |
| SCHEMBL19049449 | 0.70 | KDM4E (0.49) | KDM4EMAPTHSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033270-A2 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |