⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11348671 | 0.85 | ALDH1A1 (0.53) | — | |
| SCHEMBL11938145 | 0.82 | ALDH1A1 (0.50) | — | |
| SCHEMBL12039646 | 0.82 | — | — | |
| SCHEMBL18848571 | 0.79 | TSHR (0.38) | — | |
| SCHEMBL7762905 | 0.77 | ALDH1A1 (0.59) | — | |
| SCHEMBL9150341 | 0.76 | — | — | |
| SCHEMBL3076033 | 0.75 | — | — | |
| SCHEMBL28537177 | 0.75 | TSHR (0.52) | — | |
| SCHEMBL5604843 | 0.74 | TDP1 (0.48) | — | |
| SCHEMBL5604639 | 0.74 | ALDH1A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017117530-A9 | IONIZABLE CATIONIC LIPID | ARCTURUS THERAPEUTICS, INC. (US) | 2021-03-11 | — | — | WO | disclosed |
| WO-2018068010-A1 | HIGHLY POTENT MULTIMERIC E-SELECTIN ANTAGONISTS | GLYCOMIMETICS, INC. (US) | 2018-04-12 | — | — | WO | disclosed |
| EP-2814834-B1 | C-3 CYCLOALKENYL TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY | VIIV HEALTHCARE UK (NO 5) LTD (GB) | 2017-09-13 | — | — | EP | disclosed |
| WO-2017117530-A1 | IONIZABLE CATIONIC LIPID | ARCTURUS THERAPEUTICS, INC. (US) | 2017-07-06 | — | — | WO | disclosed |
| WO-2013033270-A2 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |