Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.68 |
| ▸ | P2RY10 | O00398 | 8/20 | 0.62 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.62 |
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
| ▸ | FABP3 | P05413 | 1/20 | 0.50 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21581301 | 0.93 | P2RY10 (0.67) | DNM1P2RY10GPR34LPAR6LPAR1 | |
| SCHEMBL25850732 | 0.90 | DNM1 (0.66) | DNM1P2RY10GPR34DGKAFABP3 | |
| SCHEMBL12629387 | 0.87 | P2RY10 (0.69) | P2RY10GPR34DGKAFABP3 | |
| SCHEMBL26062154 | 0.86 | P2RY10 (0.68) | DNM1P2RY10GPR34DGKAFABP3 | |
| SCHEMBL26061604 | 0.85 | DNM1 (0.48) | DNM1P2RY10GPR34FABP3LPAR1 | |
| SCHEMBL17817012 | 0.84 | LPAR3 (0.58) | DNM1P2RY10LPAR1LPAR5LPAR2 | |
| SCHEMBL14355841 | 0.84 | LPAR3 (0.58) | DNM1P2RY10LPAR1LPAR5LPAR2 | |
| SCHEMBL13854647 | 0.84 | DNM1 (0.57) | DNM1P2RY10GPR34FABP3LPAR6 | |
| SCHEMBL13854630 | 0.84 | LPAR1 (0.67) | DNM1P2RY10GPR34LPAR6LPAR1 | |
| SCHEMBL14047328 | 0.84 | DNM1 (0.57) | DNM1P2RY10GPR34FABP3LPAR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013032643-A2 | LIPIDS CAPABLE OF CONFORMATIONAL CHANGE AND THEIR USE IN FORMULATIONS TO DELIVER THERAPEUTIC AGENTS TO CELLS | DICERNA PHARMACEUTICALS, INC. (US) | 2013-03-07 | — | — | WO | disclosed |