Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.70 |
| ▸ | P2RY10 | O00398 | 8/20 | 0.64 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.56 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.56 |
| ▸ | DGKA | P23743 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CDC25A | P30304 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26061597 | 1.00 | FABP3 (0.70) | FABP3P2RY10GPR34SMN1; SMN2NR5A2 | |
| SCHEMBL25665820 | 1.00 | FABP3 (0.70) | FABP3P2RY10GPR34SMN1; SMN2NR5A2 | |
| SCHEMBL26018724 | 1.00 | FABP3 (0.70) | FABP3P2RY10GPR34SMN1; SMN2NR5A2 | |
| SCHEMBL14448112 | 0.97 | FABP3 (0.70) | FABP3P2RY10GPR34SMN1; SMN2NR5A2 | |
| SCHEMBL3629744 | 0.93 | FABP3 (0.72) | FABP3P2RY10GPR34SMN1; SMN2NR5A2 | |
| SCHEMBL3630629 | 0.93 | FABP3 (0.72) | FABP3P2RY10GPR34SMN1; SMN2NR5A2 | |
| SCHEMBL3631867 | 0.93 | FABP3 (0.72) | FABP3P2RY10GPR34SMN1; SMN2NR5A2 | |
| SCHEMBL14669245 | 0.93 | P2RY10 (0.68) | FABP3P2RY10GPR34 | |
| SCHEMBL12629387 | 0.88 | P2RY10 (0.69) | FABP3P2RY10GPR34DGKA | |
| SCHEMBL15968278 | 0.88 | LMNA (0.71) | FABP3SMN1; SMN2NR5A2NR5A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013032643-A2 | LIPIDS CAPABLE OF CONFORMATIONAL CHANGE AND THEIR USE IN FORMULATIONS TO DELIVER THERAPEUTIC AGENTS TO CELLS | DICERNA PHARMACEUTICALS, INC. (US) | 2013-03-07 | — | — | WO | disclosed |