SCHEMBL14758809

SCHEMBL14758809

NC(=O)c1cc(-c2ccc(Cl)c(Cl)c2)ncn1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KMO O15229 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1939274 0.86 KMO (1.00) KMO
SCHEMBL14742293 0.86 KMO (0.77) KMO
SCHEMBL14742105 0.84 KMO (0.75) KMO
SCHEMBL2229010 0.84 KMO (0.66) KMO
SCHEMBL1938831 0.84 KMO (0.97) KMO
SCHEMBL1938828 0.84 KMO (0.97) KMO
SCHEMBL1938830 0.83 KMO (0.73) KMO
SCHEMBL2225344 0.82 KMO (0.62) KMO
SCHEMBL14742157 0.82 KMO (0.71) KMO
SCHEMBL6917895 0.82 KMO (0.62) KMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013033068-A1 KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF COURTNEY STEPHEN MARTIN (GB) 2013-03-07 WO disclosed