Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 1.00 |
| ▸ | DRD1 | P21728 | 1/20 | 1.00 |
| ▸ | BCHE | P06276 | 1/20 | 0.82 |
| ▸ | ACHE | P22303 | 1/20 | 0.82 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | DRD4 | P21917 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (R)-Reticuline SCHEMBL29373552 | 1.00 | DRD2 (1.00) | DRD2DRD1BCHEACHEKCNH2 | |
| (S)-Reticuline SCHEMBL147596 | 1.00 | DRD2 (1.00) | DRD2DRD1BCHEACHEKCNH2 | |
| (R)-Reticuline SCHEMBL29364903 | 1.00 | DRD2 (1.00) | DRD2DRD1BCHEACHEKCNH2 | |
| (R)-Reticuline SCHEMBL9587509 | 1.00 | DRD2 (1.00) | DRD2DRD1BCHEACHEKCNH2 | |
| (S)-Reticuline SCHEMBL29923953 | 1.00 | DRD2 (1.00) | DRD2DRD1BCHEACHEKCNH2 | |
| Laudanidine SCHEMBL18187574 | 0.98 | DRD2 (0.95) | DRD2DRD1BCHEACHEKCNH2 | |
| Codamine SCHEMBL15696578 | 0.95 | DRD2 (0.91) | DRD2DRD1BCHEACHEKCNH2 | |
| Codamine SCHEMBL680513 | 0.95 | DRD2 (0.91) | DRD2DRD1BCHEACHEKCNH2 | |
| Laudanidine SCHEMBL15696580 | 0.95 | DRD2 (0.91) | DRD2DRD1BCHEACHEKCNH2 | |
| Codamine SCHEMBL30720053 | 0.95 | DRD2 (0.91) | DRD2DRD1BCHEACHEKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1098 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388939-A1 | RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF L-DOPA, DOPAMINE, S-NOROCLAURINE OR DERIVATIVES THEREOF | RIVER STONE BIOTECH APS (DK) | 2025-12-25 | — | — | US | claimed |
| US-12497638-B2 | Methods of producing epimerases and benzylisoquinoline alkaloids | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-12-16 | — | — | US | claimed |
| EP-4615963-A1 | GENETICALLY MODIFIED BENZYLISOQUINOLINE ALKALOID-PRODUCING HOST CELLS WITH MODIFIED EFFLUX TRANSPORTER GENE EXPRESSION | River Stone Biotech ApS (DK) | 2025-09-17 | — | — | EP | claimed |
| US-12371722-B2 | Recombinant host cells with improved production of L-DOPA, dopamine, S-noroclaurine or derivatives thereof | RIVER STONE BIOTECH APS (DK) | 2025-07-29 | — | — | US | claimed |
| US-12359233-B2 | Production method of (R)-reticuline | FERMELANTA, INC. (JP) | 2025-07-15 | — | — | US | claimed |
| CN-119709674-A | Berberine bridge enzyme mutant and application thereof in synthesis of (S) -scolerine | 江南大学 | 2025-03-28 | — | — | CN | claimed |
| CN-119570825-A | Method for efficiently synthesizing protoberberine compounds and application thereof | 中国科学院分子植物科学卓越创新中心 | 2025-03-07 | — | — | CN | claimed |
| WO-2025031833-A1 | RECOMBINANT STRAIN AND USE THEREOF IN PRODUCTION OF SCOULERINE | CHRYSEA LIMITED (IE) | 2025-02-13 | — | — | WO | claimed |
| WO-2024194018-A1 | METHOD FOR PRODUCING CORYTUBERINE AND SALUTARIDINE | Universität Graz (AT) | 2024-09-26 | — | — | WO | claimed |
| EP-4431612-A1 | PROCESS FOR THE PREPARATION OF CORORYLOURIN AND SALUTARIDINE | Universität Graz (AT) | 2024-09-18 | — | — | EP | claimed |
| WO-1997014713-A1 | AMPHIPHILIC COMPLEXES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SUCH COMPLEXES | COLETICA (FR) | 1997-04-24 | — | — | WO | claimed |
| EP-0461201-B1 | PROSTHETIC MENISCUS | REGEN BIOLOG INC (US) | 1995-07-26 | — | — | EP | claimed |
| EP-0638104-A1 | UNDECYLENIC ACID DERIVATIVES WITH HYDROPHILIC MOLECULES AND UTILIZATIONS IN COSMETICS OR IN PHARMACY | COLETICA (FR) | 1995-02-15 | — | — | EP | claimed |
| WO-1993022370-A1 | UNDECYLENIC ACID DERIVATIVES WITH HYDROPHILIC MOLECULES AND UTILIZATIONS IN COSMETICS OR IN PHARMACY | COLETICA (FR) | 1993-11-11 | — | — | WO | claimed |
| EP-0237398-B1 | USE OF BIOLOGICALLY ACTIVE POLYPEPTIDES AND COMPOSITIONS CONTAINING THEM | LVMH RECHERCHE (FR) | 1992-07-01 | — | — | EP | claimed |
| EP-0143809-B1 | METHOD FOR OBTAINING HUMAN HEPATOCYTES CULTURES, CULTURES OBTAINED THEREBY AND BIOLOGICAL AND BIOCHEMICAL APPLICATIONS THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1989-01-18 | — | — | EP | claimed |
| EP-0237398-A1 | Use of biologically active polypeptides and compositions containing them | LVMH RECHERCHE (FR) | 1987-09-16 | — | — | EP | claimed |
| EP-0143809-A1 | METHOD FOR OBTAINING HUMAN HEPATOCYTES CULTURES, CULTURES OBTAINED THEREBY AND BIOLOGICAL AND BIOCHEMICAL APPLICATIONS THEREOF. | INST NAT SANTE RECH MED (FR) | 1985-06-12 | — | — | EP | claimed |
| WO-1984004325-A1 | METHOD FOR OBTAINING HUMAN HEPATOCYTES CULTURES, CULTURES OBTAINED THEREBY AND BIOLOGICAL AND BIOCHEMICAL APPLICATIONS THEREOF | INST NAT SANTE RECH MED (FR) | 1984-11-08 | — | — | WO | claimed |
| US-3945746-A | Grating structure for roadway storm drain inlets and the like | MARYLAND GRADING AND FABRICATING COMPANY, INC. (US) | 1976-03-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388939-A1 | RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF L-DOPA, DOPAMINE, S-NOROCLAURINE OR DERIVATIVES THEREOF | DBH, DDT, COMT | DRD2 989/4885DRD1 1205/4885BCHE 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.