Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28137682 | 0.69 | CYP19A1 (0.34) | CES2CES1EPHX1EPHX2NPC1 | |
| SCHEMBL6053988 | 0.69 | CES2 (0.33) | CES2CES1EPHX1EPHX2NPC1 | |
| SCHEMBL6054051 | 0.69 | CES2 (0.33) | CES2CES1EPHX1EPHX2NPC1 | |
| SCHEMBL14759962 | 0.69 | CES2 (0.33) | CES2CES1EPHX1EPHX2NPC1 | |
| SCHEMBL3886562 | 0.69 | CYP19A1 (0.34) | CES2CES1EPHX1EPHX2NPC1 | |
| SCHEMBL476001 | 0.67 | CES2 (0.32) | CES2CES1EPHX1 | |
| SCHEMBL6054000 | 0.67 | MAPK1 (0.33) | CES2CES1EPHX1TSHR | |
| SCHEMBL22200087 | 0.63 | — | — | |
| SCHEMBL8955463 | 0.63 | CYP1A2 (0.37) | — | |
| SCHEMBL9333616 | 0.63 | NR1H2 (0.31) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072647-A1 | OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF | PETROCHINA COMPANY LIMITED (CN) | 2013-03-21 | — | — | US | claimed |
| EP-2567986-A1 | OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF | Petrochina Company Limited (CN) | 2013-03-13 | — | — | EP | claimed |
| CN-102746426-A | Olefin polymerization catalyst, preparation and application thereof | PETROCHINA CO LTD | 2012-10-24 | — | — | CN | claimed |
| US-20130072647-A1 | OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF | PETROCHINA COMPANY LIMITED (CN) | 2013-03-21 | — | — | US | disclosed |
| EP-2567986-A1 | OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF | Petrochina Company Limited (CN) | 2013-03-13 | — | — | EP | disclosed |
| CN-102746426-A | Olefin polymerization catalyst, preparation and application thereof | PETROCHINA CO LTD | 2012-10-24 | — | — | CN | disclosed |