Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14760022 | 0.87 | GRIK1 (0.31) | — | |
| SCHEMBL15662680 | 0.75 | HMGCR (0.37) | HMGCRPTPN7ALDH1A1RECQLTDP1 | |
| SCHEMBL588584 | 0.72 | TSHR (0.39) | HMGCRPTPN7ALDH1A1RECQLTDP1 | |
| Oxalic Acid SCHEMBL5367389 | 0.72 | HMGCR (0.38) | HMGCRPTPN7ALDH1A1RECQLTDP1 | |
| SCHEMBL10566659 | 0.69 | TSHR (0.41) | HMGCRPTPN7ALDH1A1RECQLTDP1 | |
| Bicarbonate SCHEMBL15967929 | 0.69 | PTPN7 (0.60) | HMGCRPTPN7ALDH1A1RECQLTDP1 | |
| SCHEMBL996455 | 0.69 | — | — | |
| SCHEMBL10566631 | 0.66 | TSHR (0.38) | HMGCRPTPN7TSHR | |
| SCHEMBL9794741 | 0.66 | TSHR (0.38) | HMGCRPTPN7TDP1TSHR | |
| SCHEMBL16594184 | 0.66 | HMGCR (0.47) | HMGCRPTPN7ALDH1A1RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072647-A1 | OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF | PETROCHINA COMPANY LIMITED (CN) | 2013-03-21 | — | — | US | claimed |
| EP-2567986-A1 | OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF | Petrochina Company Limited (CN) | 2013-03-13 | — | — | EP | claimed |
| US-20130072647-A1 | OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF | PETROCHINA COMPANY LIMITED (CN) | 2013-03-21 | — | — | US | disclosed |
| EP-2567986-A1 | OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF | Petrochina Company Limited (CN) | 2013-03-13 | — | — | EP | disclosed |