Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051547 | 0.94 | CYP4F2 (0.46) | CYP4F2CYP4A11ACLYZDHHC20ZDHHC2 | |
| SCHEMBL19469710 | 0.94 | CYP4F2 (0.46) | CYP4F2CYP4A11ACLYZDHHC20ZDHHC2 | |
| SCHEMBL35755 | 0.94 | CYP4F2 (0.46) | CYP4F2CYP4A11ACLYZDHHC20ZDHHC2 | |
| SCHEMBL15416699 | 0.92 | CYP4F2 (0.43) | CYP4F2CYP4A11ACLYZDHHC20ZDHHC2 | |
| SCHEMBL9343712 | 0.88 | CYP4F2 (0.45) | CYP4F2CYP4A11ACLYZDHHC20ZDHHC2 | |
| SCHEMBL7194742 | 0.87 | CYP4F2 (0.41) | CYP4F2CYP4A11ACLYZDHHC20ZDHHC2 | |
| SCHEMBL245767 | 0.85 | TSHR (0.50) | CYP4F2CYP4A11POLBTSHRMAPT | |
| SCHEMBL31443245 | 0.81 | CYP4F2 (0.37) | CYP4F2CYP4A11ZDHHC20ZDHHC2CYP3A4 | |
| SCHEMBL6231011 | 0.80 | CA2 (0.45) | CYP4F2CYP4A11TSHRMAPTMEN1 | |
| SCHEMBL24059245 | 0.80 | TSHR (0.39) | ZDHHC20ZDHHC2CYP3A4GMNNUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2567999-B1 | Silicone containing compositions and uses thereof | AIR PROD & CHEM (US) | 2014-07-02 | — | — | EP | disclosed |
| US-8735524-B2 | Silicone containing compositions and uses thereof | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-05-27 | — | — | US | disclosed |
| US-20130065998-A1 | Silicone Containing Compositions and Uses Thereof | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2013-03-14 | — | — | US | disclosed |
| EP-2567999-A1 | Silicone containing compositions and uses thereof | Air Products and Chemicals, Inc. (US) | 2013-03-13 | — | — | EP | disclosed |