SCHEMBL14760424

SCHEMBL14760424

C=CC(=O)C1(C(=O)c2ccccc2)C=CC=CC1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.40
LMNA P02545 1/20 0.33
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
TGM2 P21980 1/20 0.30
MAPK1 P28482 2/20 0.30
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7165670 0.80 LMNA (0.38) LMNACA2CA4MAPK1ALDH1A1
SCHEMBL3808936 0.73 AKT1 (0.37) AKT1LMNA
SCHEMBL8344242 0.73 LMNA (0.37) AKT1LMNACA2CA4MAPK1
SCHEMBL7560765 0.72 AKT1 (0.35) AKT1LMNACA2CA4MAPK1
SCHEMBL534047 0.71 LMNA (0.38) LMNACA2CA4MAPK1ALDH1A1
SCHEMBL7897223 0.70 LMNA (0.40) LMNACA2CA4MAPK1ALDH1A1
SCHEMBL174540 0.70 LMNA (0.37) LMNACA2CA4MAPK1ALDH1A1
SCHEMBL4525725 0.70 LMNA (0.37) LMNACA2CA4MAPK1ALDH1A1
SCHEMBL27981903 0.70 LMNA (0.37) LMNACA2CA4MAPK1ALDH1A1
SCHEMBL27904507 0.70 LMNA (0.37) LMNACA2CA4MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2291480-B1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE TAPE 3M INNOVATIVE PROPERTIES CO (US) 2013-03-13 EP claimed