Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.39 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1069940 | 0.90 | BACE1 (0.56) | BACE1ESR2ALDH1A1HPGDBCL2L1 | |
| SCHEMBL72006 | 0.83 | TP53 (0.50) | ESR2ALDH1A1HPGDHSD17B10ESR1 | |
| SCHEMBL19086326 | 0.77 | ESR2 (0.50) | BACE1ESR2ALDH1A1ALOX5 | |
| SCHEMBL21409958 | 0.76 | HSD17B1 (0.59) | BACE1ESR2ALDH1A1HPGDBCL2L1 | |
| SCHEMBL13799732 | 0.76 | ESR1 (0.44) | BACE1ESR2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL19314239 | 0.73 | TP53 (0.41) | ESR2ALDH1A1HPGDHSD17B10ESR1 | |
| SCHEMBL14760441 | 0.72 | ESR1 (0.53) | BACE1ESR2ALDH1A1ESR1PELI1 | |
| SCHEMBL4274407 | 0.72 | BACE1 (0.73) | BACE1ESR2ALDH1A1HPGDBCL2L1 | |
| SCHEMBL22888341 | 0.72 | BACE1 (0.65) | BACE1ESR2ALDH1A1HPGDBCL2L1 | |
| SCHEMBL27989580 | 0.71 | ESR2 (0.56) | BACE1ESR2ALDH1A1HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277936-B1 | Method of preparing polycarbonate resin | LG CHEMICAL LTD (KR) | 2013-03-13 | — | — | EP | disclosed |