Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | NAT1 | P18440 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14760982 | 0.75 | MIF (0.41) | MIFTRIM24TRIM33NAT1CA2 | |
| SCHEMBL17691388 | 0.62 | MIF (0.64) | MIFNFKB1MEN1ALDH1A1KMT2A | |
| SCHEMBL3581744 | 0.62 | MIF (0.64) | MIFNFKB1MEN1ALDH1A1KMT2A | |
| SCHEMBL17691411 | 0.62 | IKBKB (0.64) | MIFTRIM24TRIM33NAT1PLK4 | |
| SCHEMBL3581740 | 0.62 | MIF (0.64) | MIFNFKB1MEN1ALDH1A1KMT2A | |
| SCHEMBL7132282 | 0.61 | IKBKB (0.65) | MIFTRIM24TRIM33NAT1L3MBTL1 | |
| SCHEMBL1524256 | 0.61 | ALDH1A1 (0.58) | MIFTRIM24TRIM33NAT1NFKB1 | |
| SCHEMBL5585089 | 0.61 | ALDH1A1 (0.61) | MIFTRIM24TRIM33NAT1ALDH1A1 | |
| SCHEMBL17691431 | 0.61 | IKBKB (0.65) | MIFTRIM24TRIM33NAT1L3MBTL1 | |
| SCHEMBL14571661 | 0.61 | ALDH1A1 (0.61) | MIFTRIM24TRIM33NAT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9504641-B2 | Therapy to reduce extravasation damage | PTLNV, LLC, SERIES 6 | 2016-11-29 | — | — | US | disclosed |
| US-20130064865-A1 | THERAPY TO REDUCE EXTRAVASATION DAMAGE | PTLNV, LLC, SERIES 6 | 2013-03-14 | — | — | US | disclosed |