⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1686520 | 0.77 | C1R (0.43) | — | |
| SCHEMBL19548224 | 0.74 | — | — | |
| SCHEMBL1459723 | 0.72 | — | — | |
| SCHEMBL991182 | 0.72 | — | — | |
| SCHEMBL31126634 | 0.72 | — | — | |
| SCHEMBL1441896 | 0.72 | — | — | |
| SCHEMBL6401 | 0.72 | — | — | |
| SCHEMBL6045282 | 0.72 | — | — | |
| SCHEMBL13184883 | 0.72 | — | — | |
| SCHEMBL31522555 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110845439-B | Method for synthesizing 2-substituted benzothiazole by one-pot method | 南京工业大学 | 2023-04-11 | — | — | CN | disclosed |
| CN-109863147-A | Compound and application thereof with ERK kinase inhibiting activity | 上海海和药物研究开发有限公司 | 2019-06-07 | — | — | CN | disclosed |
| CN-105330698-B | Loop coil aryl phosphorous oxides and sulfide | 齐鲁制药有限公司 | 2019-05-28 | — | — | CN | disclosed |
| CN-109790157-A | New antimicrobial compound | 方济各安吉利克化学联合股份有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-106866543-B | A method of benzimidazole compound is catalyzed and synthesized under microwave radiation in water phase | 福建医科大学 | 2019-05-14 | — | — | CN | disclosed |
| CN-109415373-A | New antimicrobial compound | 方济各安吉利克化学联合股份有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-106432074-B | A method of 4- aryl -2- quinolinone is prepared by carbon dioxide | 常州大学 | 2019-01-29 | — | — | CN | disclosed |
| CN-108883103-A | PIPERIDINYL NOCICEPTIN RECEPTOR COMPOUNDS | 阿斯特来亚治疗有限责任公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108558753-A | The method that carbostyril compound is prepared as CO source of releases using iron pentacarbonyl | 陕西师范大学 | 2018-09-21 | — | — | CN | disclosed |
| CN-108430471-A | Factor xia inhibitors | 默沙东公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-103974938-A | Substituted tetrahydroisoquinoline compounds as factor xia inhibitors | BRISTOL MYERS SQUIBB CO | 2014-08-06 | — | — | CN | disclosed |
| CN-103342705-A | Method for synthesizing pyrrole [1,2-a ] quinoxaline derivative | NANJING UNIVERSITY OF TECHNOLOGY | 2013-10-09 | — | — | CN | disclosed |
| CN-103333171-A | Synthetic method of pyrrole [1,2-a ] quinoxaline derivative | NANJING UNIVERSITY OF TECHNOLOGY | 2013-10-02 | — | — | CN | disclosed |
| CN-103261156-A | New compounds for the treatment of neurodegenerative diseases | LEUVEN K U RES & DEV | 2013-08-21 | — | — | CN | disclosed |
| WO-2013036232-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF MYELOPROLIFERATIVE DISEASES AND OTHER PROLIFERATIVE DISEASES | DECIPHERA PHARMACEUTICALS, LLC (US) | 2013-03-14 | — | — | WO | disclosed |
| CN-102361857-A | Novel cyclic benzimidazole derivatives useful anti-diabetic agents | MERCK SHARP & DOHME | 2012-02-22 | — | — | CN | disclosed |
| CN-102164900-A | 3-amino-indazole or 3-amino-4,5,6,7-tetrahydro-indazole derivatives | HOFFMANN LA ROCHE | 2011-08-24 | — | — | CN | disclosed |
| CN-102060888-A | Novel compounds | TANABE SEIYAKU CO | 2011-05-18 | — | — | CN | disclosed |
| CN-101151245-A | Indan-amide derivatives with glycogen phosphorylase inhibitory activity | ASTRAZENECA AB (SE) | 2008-03-26 | — | — | CN | disclosed |
| CN-1829728-A | Novel compounds | TANABE SEIYAKU CO (JP) | 2006-09-06 | — | — | CN | disclosed |