⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31522555 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL1841937 | 0.97 | TDP1 (0.46) | — | |
| Oxalic Acid SCHEMBL1660697 | 0.87 | SIGMAR1 (0.41) | — | |
| SCHEMBL7941500 | 0.79 | TDP1 (0.35) | — | |
| SCHEMBL1537798 | 0.78 | ALDH1A1 (0.52) | — | |
| SCHEMBL31484713 | 0.78 | ALDH1A1 (0.52) | — | |
| SCHEMBL1686520 | 0.77 | C1R (0.43) | — | |
| SCHEMBL19548224 | 0.74 | — | — | |
| SCHEMBL23865497 | 0.72 | ALDH1A1 (0.43) | — | |
| SCHEMBL6401 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250082593-A1 | HALOALLYLAMINE SULFONE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | SYNTARA LIMITED (AU) | 2025-03-13 | — | — | US | disclosed |
| US-12178791-B2 | Haloallylamine sulfone derivative inhibitors of lysyl oxidases and uses thereof | SYNTARA LIMITED (AU) | 2024-12-31 | — | — | US | disclosed |
| EP-3829520-B1 | HALOALLYLAMINE SULFONE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | SYNTARA LTD (AU) | 2024-11-27 | — | — | EP | disclosed |
| CN-112533897-B | Halogenated allylamine sulfone derivative inhibitors of lysyl oxidase and uses thereof | 法玛西斯有限公司 | 2023-07-14 | — | — | CN | disclosed |
| US-20230099441-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | GENEROS BIOPHARMA LTD. (CN) | 2023-03-30 | — | — | US | disclosed |
| US-20220024924-A1 | SOLID STATE FORMS OF LUMATEPERONE SALTS AND PROCESSES FOR PREPARATION OF LUMATEPERONE AND SALTS THEREOF | ASSIA CHEMICAL INDUSTRIES LTD. (IL) | 2022-01-27 | — | — | US | disclosed |
| US-20210353571-A1 | HALOALLYLAMINE SULFONE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | SYNTARA LIMITED (AU) | 2021-11-18 | — | — | US | disclosed |
| US-20210353571-A1 | HALOALLYLAMINE SULFONE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | SYNTARA LIMITED (AU) | 2021-11-18 | — | — | US | disclosed |
| EP-3829520-A1 | HALOALLYLAMINE SULFONE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | Pharmaxis Ltd. (AU) | 2021-06-09 | — | — | EP | disclosed |
| CN-112533897-A | Haloallylamine sulfone derivative inhibitors of lysyl oxidase and uses thereof | 法玛西斯有限公司 | 2021-03-19 | — | — | CN | disclosed |
| EP-0912899-A1 | ENHANCED CHROMATOGRAPHY USING MULTIPHOTON DETECTION | Biotraces, Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| US-5852030-A | Indole derivatives, process for producing the same and medicinal uses of the same | TORAY INDUSTRIES, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| WO-1998002750-A1 | ENHANCED CHROMATOGRAPHY USING MULTIPHOTON DETECTION | BIOTRACES, INC. (US) | 1998-01-22 | — | — | WO | disclosed |
| US-5436249-A | Opioid agonist compounds | G. D. SEARLE & CO. (US) | 1995-07-25 | — | — | US | disclosed |
| US-5354863-A | Analgesics | G. D. SEARLE & CO. (US) | 1994-10-11 | — | — | US | disclosed |
| CN-1092425-A | Indole derivatives, its manufacture method and medicinal use thereof | TORAY INDUSTRIES (JP) | 1994-09-21 | — | — | CN | disclosed |
| EP-0614898-A1 | INDOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1994-09-14 | — | — | EP | disclosed |
| US-5225417-A | Analgesics | G. D. SEARLE & CO. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0242685-A2 | Oxidative release of photographically useful groups from hydrazide compounds | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-10-28 | — | — | EP | disclosed |
| EP-0019587-B1 | CARBOXYLIC ACID HYDRAZIDES, PROCESS FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1983-07-20 | — | — | EP | disclosed |