Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.34 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17277451 | 0.87 | SLC6A2 (0.48) | SLC6A2SLC6A4KCNH2SLC6A3CACNA1B | |
| SCHEMBL12062136 | 0.85 | SLC6A2 (0.46) | SLC6A2SLC6A4KCNH2SLC6A3PSEN1 | |
| SCHEMBL20082493 | 0.74 | SLC6A2 (0.48) | SLC6A2SLC6A4KCNH2SLC6A3PSEN1 | |
| SCHEMBL17277329 | 0.74 | SLC6A2 (0.49) | SLC6A2SLC6A4KCNH2SLC6A3CACNA1B | |
| SCHEMBL12062182 | 0.71 | SLC6A2 (0.47) | SLC6A2SLC6A4KCNH2SLC6A3PSEN1 | |
| SCHEMBL17277309 | 0.70 | HTR2A (0.44) | SLC6A2SLC6A4KCNH2SLC6A3HTR7 | |
| SCHEMBL17277595 | 0.69 | SLC6A2 (0.49) | SLC6A2SLC6A4KCNH2SLC6A3CACNA1B | |
| SCHEMBL17277488 | 0.69 | HTR2A (0.49) | SLC6A2SLC6A4KCNH2SLC6A3CACNA1B | |
| SCHEMBL12075657 | 0.69 | SLC6A2 (0.48) | SLC6A2SLC6A4KCNH2SLC6A3CACNA1B | |
| SCHEMBL17277566 | 0.69 | SLC6A2 (0.48) | SLC6A2SLC6A4KCNH2SLC6A3CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047319-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |