Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835772 | 0.82 | KMT2A (0.64) | ELANEKMT2AATMESR1HIF1A | |
| Butane SCHEMBL15309676 | 0.79 | ELANE (0.61) | ELANEKMT2AATMESR1HIF1A | |
| SCHEMBL8835840 | 0.79 | ELANE (0.58) | ELANEKMT2AATMESR1HIF1A | |
| SCHEMBL56436 | 0.79 | ELANE (0.69) | ELANEKMT2AATMSMN1; SMN2POLB | |
| SCHEMBL14048482 | 0.79 | ELANE (0.61) | ELANEKMT2AATMESR1HIF1A | |
| SCHEMBL1320881 | 0.78 | ELANE (0.65) | ELANEKMT2AATMESR1HIF1A | |
| SCHEMBL8966108 | 0.78 | ELANE (0.69) | ELANEKMT2AATMSMN1; SMN2POLB | |
| SCHEMBL15064112 | 0.78 | ELANE (0.86) | ELANEKMT2AATMMAPTRAB9A | |
| SCHEMBL15087045 | 0.78 | ELANE (0.69) | ELANEKMT2AATMESR1HIF1A | |
| SCHEMBL13133147 | 0.78 | ELANE (0.69) | ELANEKMT2AATMESR1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9668946-B2 | Dental materials based on monomers having debonding-on-demand properties | IVOCLAR VIVADENT AG (LI) | 2017-06-06 | — | — | US | disclosed |
| US-20140329929-A1 | DENTAL MATERIALS BASED ON MONOMERS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2014-11-06 | — | — | US | disclosed |
| WO-2013034777-A2 | DENTAL MATERIALS BASED ON MONOMERS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2013-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140329929-A1 | DENTAL MATERIALS BASED ON MONOMERS HAVING DEBONDING-ON-DEMAND PROPERTIES | RCOR3, NR2E1, RER1 | ELANE 4068/4885KMT2A 417/4885ATM 3481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.