SCHEMBL14764369

SCHEMBL14764369

Cc1cn(C2O[C@H](CO)[C@@H](O)[C@H]2I)c(=O)[nH]c1=O

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.59
TK2 O00142 4/20 0.58
TYMP P19971 5/20 0.57
ALDH1A1 P00352 1/20 0.56
LMNA P02545 1/20 0.56
ALB P02768 1/20 0.56
POLB P06746 1/20 0.56
ADRA1A P35348 1/20 0.56
BLM P54132 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16566735 1.00 PYGM (0.59) PYGMTK2TYMPALDH1A1LMNA
SCHEMBL2585414 1.00 PYGM (0.59) PYGMTK2TYMPALDH1A1LMNA
SCHEMBL2585408 1.00 PYGM (0.59) PYGMTK2TYMPALDH1A1LMNA
SCHEMBL2585412 1.00 PYGM (0.59) PYGMTK2TYMPALDH1A1LMNA
SCHEMBL21351104 1.00 PYGM (0.59) PYGMTK2TYMPALDH1A1LMNA
SCHEMBL23813661 1.00 PYGM (0.59) PYGMTK2TYMPALDH1A1LMNA
SCHEMBL2579335 0.90 PYGM (0.59) PYGMTK2TYMPALDH1A1LMNA
SCHEMBL2579331 0.90 PYGM (0.59) PYGMTK2TYMPALDH1A1LMNA
SCHEMBL2579333 0.90 PYGM (0.59) PYGMTK2TYMPALDH1A1LMNA
SCHEMBL10340724 0.88 PYGM (0.70) PYGMTK2TYMPALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013036868-A1 SYNTHESIS AND USES OF NUCLEIC ACID COMPOUNDS WITH CONFORMATIONALLY RESTRICTED MONOMERS MARINA BIOTECH INC. (US) 2013-03-14 WO disclosed