⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4765510 | 0.68 | — | — | |
| SCHEMBL13134064 | 0.68 | — | — | |
| SCHEMBL4314716 | 0.68 | — | — | |
| SCHEMBL17760163 | 0.68 | — | — | |
| SCHEMBL29771392 | 0.68 | — | — | |
| SCHEMBL8117344 | 0.68 | — | — | |
| SCHEMBL19235153 | 0.64 | — | — | |
| SCHEMBL17734068 | 0.64 | — | — | |
| SCHEMBL8331195 | 0.64 | — | — | |
| SCHEMBL10964048 | 0.61 | NISCH (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103906512-A | Tetracyclic heterocyclic compounds and methods of use thereof for treating viral diseases | MERCK SHARP & DOHME | 2014-07-02 | — | — | CN | disclosed |
| WO-2013033971-A1 | TETRACYCLIC HETEROCYCLE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME CORP. (US) | 2013-03-14 | — | — | WO | disclosed |