⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13134064 | 0.68 | — | — | |
| SCHEMBL29771392 | 0.68 | — | — | |
| SCHEMBL4765510 | 0.68 | — | — | |
| SCHEMBL17760163 | 0.68 | — | — | |
| SCHEMBL14764412 | 0.68 | — | — | |
| SCHEMBL8117344 | 0.68 | — | — | |
| SCHEMBL19235153 | 0.64 | — | — | |
| SCHEMBL17734068 | 0.64 | — | — | |
| SCHEMBL8331195 | 0.64 | — | — | |
| SCHEMBL18573300 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437100-A | Preparation method and application of novel ionic salicylaldehyde Schiff base zirconium complex | UNIV SHANXI MEDICAL | 2019-11-12 | — | — | CN | claimed |
| CN-109134330-A | The asymmetric preparation method of amino acid derived chiral catalyst, 3,4- dihydropyrimidine-2-keto derivative | 浙江工业大学上虞研究院有限公司 | 2019-01-04 | — | — | CN | claimed |
| CN-108191771-A | A kind of 3,4- dihydropyrimidine-2-ketos class function monomer and polymer and its their preparation method | 清华大学 | 2018-06-22 | — | — | CN | claimed |
| CN-106632071-A | Preparation method of 3, 4-dihydropyrimidine-2-ketone derivative through high-efficient catalyzation of ethyl alcohol promoted titanocene dichloride | 陕西师范大学 | 2017-05-10 | — | — | CN | claimed |
| CN-105712938-A | Method for synthesizing 3,4-dihydropyrimidine-2-one derivative | 台州学院 | 2016-06-29 | — | — | CN | claimed |
| CN-102814198-B | Metal/graphene nano catalyst and preparation method and application thereof | TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2016-01-20 | — | — | CN | claimed |
| EP-2958670-A1 | USE OF COMPOSITIONS OBTAINED BY CALCINING PARTICULAR METAL-ACCUMULATING PLANTS FOR IMPLEMENTING CATALYTICAL REACTIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2015-12-30 | — | — | EP | claimed |
| CN-104774297-A | High-polymer metal adhesive containing 3,4-dihydropyrimidyl-2-one structure, and preparation method and application thereof | UNIV TSINGHUA | 2015-07-15 | — | — | CN | claimed |
| CN-103319463-B | N1 substituted 3, 4-dihydropyrimidine-2-one-C60compounds and their prepn | UNIV HUNAN SCI & TECHNOLOGY | 2015-06-17 | — | — | CN | claimed |
| CN-102786527-B | Tailed porphyrin compound modified by N1-substituted 3, 4-dihydropyrimidine-2-ketone and preparation method thereof | UNIV HUNAN SCI & TECHNOLOGY | 2014-09-17 | — | — | CN | claimed |
| WO-2014128283-A1 | USE OF COMPOSITIONS OBTAINED BY CALCINING PARTICULAR METAL-ACCUMULATING PLANTS FOR IMPLEMENTING CATALYTICAL REACTIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-08-28 | — | — | WO | claimed |
| CN-103319463-A | N1 substituted 3, 4-dihydropyrimidine-2-one-C60compounds and their prepn | UNIV HUNAN SCI & TECHNOLOGY | 2013-09-25 | — | — | CN | claimed |
| CN-102814198-A | Metal/graphene nano catalyst and preparation method and application thereof | CHINESE ACAD TECH INST PHYSICS | 2012-12-12 | — | — | CN | claimed |
| CN-102153525-A | Preparation method and application of novel benzothiazole salt ionic liquid | UNIV SICHUAN | 2011-08-17 | — | — | CN | claimed |
| CN-102126720-A | Method for synthesizing graphene | CHINESE ACAD TECH INST PHYSICS | 2011-07-20 | — | — | CN | claimed |
| WO-2025136898-A1 | AGONISTS OF TREM2 ACTIVITY | MERCK SHARP & DOHME LLC (US) | 2025-06-26 | — | — | WO | disclosed |
| US-11959135-B2 | Coupling method | OXFORD NANOPORE TECHNOLOGIES PLC (GB) | 2024-04-16 | — | — | US | disclosed |
| CN-101463011-A | Process for synthesizing 3,4-dihydropyrimidine-2-keto | UNIV ZHEJIANG TECHNOLOGY (CN) | 2009-06-24 | — | — | CN | disclosed |
| CN-101367767-A | Room temperature solvent-free synthesis of 3,4-dihydropyrimidine-2-ketone | UNIV ZHEJIANG TECHNOLOGY (CN) | 2009-02-18 | — | — | CN | disclosed |
| WO-2008127291-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2008-10-23 | — | — | WO | disclosed |