SCHEMBL1476445

SCHEMBL1476445

CCCCC/C=C\C[C@@H](O)/C=C/C=C\C/C=C\CCCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OXER1 Q8TDS5 3/20 1.00
LTB4R2 Q9NPC1 2/20 0.78
MAPT P10636 2/20 0.78
ALOX5 P09917 1/20 0.78
ALDH1A1 P00352 2/20 0.74
LTB4R Q15722 1/20 0.74
FAAH O00519 3/20 0.69
PPARG P37231 2/20 0.68
KDM4E B2RXH2 1/20 0.68
MEN1 O00255 1/20 0.68
USP2 O75604 1/20 0.68
LMNA P02545 1/20 0.68
TP53 P04637 1/20 0.68
CYP3A4 P08684 1/20 0.68
HSPD1 P10809 1/20 0.68
CYP19A1 P11511 1/20 0.68
FABP4 P15090 1/20 0.68
HPGD P15428 1/20 0.68
ALOX15 P16050 1/20 0.68
CASP1 P29466 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1479725 1.00 OXER1 (1.00) OXER1LTB4R2MAPTALOX5ALDH1A1
SCHEMBL12970667 1.00 OXER1 (1.00) OXER1LTB4R2MAPTALOX5ALDH1A1
SCHEMBL1242004 1.00 OXER1 (1.00) OXER1LTB4R2MAPTALOX5ALDH1A1
SCHEMBL6382220 1.00 OXER1 (1.00) OXER1LTB4R2MAPTALOX5ALDH1A1
SCHEMBL1479722 1.00 OXER1 (1.00) OXER1LTB4R2MAPTALOX5ALDH1A1
SCHEMBL16670813 1.00 OXER1 (1.00) OXER1LTB4R2MAPTALOX5ALDH1A1
SCHEMBL15902619 1.00 OXER1 (1.00) OXER1LTB4R2MAPTALOX5ALDH1A1
SCHEMBL22607964 1.00 OXER1 (1.00) OXER1LTB4R2MAPTALOX5ALDH1A1
SCHEMBL21214020 1.00 OXER1 (1.00) OXER1LTB4R2MAPTALOX5ALDH1A1
SCHEMBL198434 1.00 OXER1 (1.00) OXER1LTB4R2MAPTALOX5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050239889-A1 In vivo release of endogenous anti-microbial mediators by leukotriene B4 (LTB4) administration GOSSELIN JEAN 2005-10-27 US claimed
US-6093741-A ANTI-NEOPLASTIC AGENT IN THE PROPHYLAXIS AND TREATMENT OF CANCERS INDUCED BY TUMOR VIRUSES AND IN OTHER NEOPLASIC DISEASES VIROCELL INC. (CA) 2000-07-25 US claimed
US-20260049331-A1 Sense-and-Response of Proteins, Peptides, and Small Molecules Using Ligand-Induced Dimerization Activating RNA Editing (LIDAR) UNIV LELAND STANFORD JUNIOR (US) 2026-02-19 US disclosed
US-20250223580-A1 PROGRAMMABLE NUCLEASE-PEPTIDASE COMPOSITIONS THE BROAD INSTITUTE, INC. 2025-07-10 US disclosed
US-20250051763-A1 METHODS AND SYSTEMS FOR CONDITIONALLY REGULATING GENE EXPRESSION FUNDACAO D. ANNA DE SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD FOUNDATION (PT) 2025-02-13 US disclosed
US-20240084335-A1 CHIMERIC PROTEINS AND METHODS OF REGULATING GENE EXPRESSION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-03-14 US disclosed
US-20240044871-A1 CHIMERIC RECEPTOR POLYPEPTIDE AND METHODS OF ACTIVATION THEREOF FUNDAÇÃO D. ANNA DE SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD FOUNDATION (PT) 2024-02-08 US disclosed
CN-109312335-B Chimeric proteins and methods of modulating gene expression 斯坦福大学托管董事会 2023-10-24 CN disclosed
US-20230321146-A1 CHIMERIC POLYPEPTIDES AND METHODS OF USING THE SAME FUNDAÇÃO D. ANNA DE SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD FOUNDATION (PT) 2023-10-12 US disclosed
US-11773411-B2 Chimeric proteins and methods of regulating gene expression THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-10-03 US disclosed
US-20230035892-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER FLAGSHIP PIONEERING, INC. 2023-02-02 US disclosed
US-20050239889-A1 In vivo release of endogenous anti-microbial mediators by leukotriene B4 (LTB4) administration GOSSELIN JEAN 2005-10-27 US disclosed
WO-2004112795-A1 LTB4 COMPOSITIONS FOR TREATING TRACT INFECTIONS LTB4 SWEDEN AB (SE) 2004-12-29 WO disclosed
US-20040208882-A1 Ltb4 as vaccine adjuvant LTB4 SWEDEN AB (SE) 2004-10-21 US disclosed
US-20040132820-A1 Agents with leukotriene B4-like antiviral (DNA) and anti-neoplastic activities GOSSELIN JEAN (CA) 2004-07-08 US disclosed
EP-1401492-A1 LTB4 AS VACCINE ADJUVANT Virocell Inc. (CA) 2004-03-31 EP disclosed
WO-2003004054-A1 LTB4 AS VACCINE ADUVANT VIROCELL INC. (CA) 2003-01-16 WO disclosed
US-6093741-A ANTI-NEOPLASTIC AGENT IN THE PROPHYLAXIS AND TREATMENT OF CANCERS INDUCED BY TUMOR VIRUSES AND IN OTHER NEOPLASIC DISEASES VIROCELL INC. (CA) 2000-07-25 US disclosed
US-5789441-A Leukotriene B4 as an antiviral and anti-neoplastic agent VIROCELL INC. (CA) 1998-08-04 US disclosed
US-5725804-A ALBUMIN PARTICLES STABLE TO RESOLUBILIZATION, POLYOXYETHYLENE GLYCOL, ALCOHOL HEMOSPHERE, INC. (US) 1998-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049331-A1 Sense-and-Response of Proteins, Peptides, and Small Molecules Using Ligand-Induced Dimerization Activating RNA Editing (LIDAR) ADAR, ZFR, SLIRP OXER1 3091/4885LTB4R2 3626/4885MAPT 3472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.