Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10974753 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL1653800 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL15228630 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL14764443 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL1421426 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL1421427 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL1114390 | 0.80 | KMT2A (0.45) | ALDH1A1KMT2ATDP1KDM4ELMNA | |
| SCHEMBL2220068 | 0.80 | MEN1 (0.52) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL2220075 | 0.80 | MEN1 (0.52) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL14764466 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013034758-A1 | SUBSTITUTED TRIAZOLOPYRAZINES AND USES THEREOF | H. LUNDBECK A/S (DK) | 2013-03-14 | — | — | WO | disclosed |