Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14937148 | 0.91 | NPC1 (0.32) | ABCB1RAB9ANPC1L3MBTL1HTT | |
| SCHEMBL6123388 | 0.90 | NPC1 (0.35) | RAB9ANPC1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL16239577 | 0.85 | ABCB1 (0.33) | ABCB1RAB9AHTTCYP3A4CYP2C9 | |
| SCHEMBL16239937 | 0.83 | ABCB1 (0.32) | ABCB1RAB9AHTTCYP3A4CYP2C9 | |
| SCHEMBL5705240 | 0.83 | NPC1 (0.39) | RAB9ANPC1SMN1; SMN2MAPTHTT | |
| SCHEMBL13003219 | 0.82 | ABCB1 (0.55) | ABCB1HTTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4659137 | 0.82 | ABCB1 (0.55) | ABCB1HTTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16239512 | 0.79 | STAT3 (0.33) | RAB9AL3MBTL1SMN1; SMN2MAPTTSHR | |
| SCHEMBL5054534 | 0.79 | F2RL3 (0.39) | RAB9ANPC1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL9905363 | 0.74 | PLK1 (0.40) | RAB9ANPC1SMN1; SMN2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013036574-A1 | MODIFIED FORMS OF PSEUDOMONAS EXOTOXIN A | INTREXON CORPORATION (US) | 2013-03-14 | — | — | WO | disclosed |