Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.31 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.31 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL573670 | 0.98 | ACHE (0.42) | ACHEMEN1USP2KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL29227043 | 0.96 | ACHE (0.45) | ACHEMEN1USP2KMT2ANPC1 | |
| Bromide SCHEMBL31481338 | 0.96 | ACHE (0.41) | ACHEMEN1USP2KMT2ANPC1 | |
| Sulfuric Acid SCHEMBL28982258 | 0.88 | ACHE (0.37) | ACHENPC1RAB9A | |
| SCHEMBL2749881 | 0.78 | ACHE (0.42) | ACHE | |
| SCHEMBL30646141 | 0.76 | CA1 (0.38) | MEN1KMT2AKDM4ECA1CA2 | |
| Iodide SCHEMBL2037554 | 0.75 | ACHE (0.46) | ACHEMEN1KMT2AAPOBEC3GKDM4E | |
| Hydrochloric Acid SCHEMBL1077570 | 0.74 | CA1 (0.40) | MEN1KMT2AKDM4ECA1CA2 | |
| SCHEMBL294564 | 0.73 | — | — | |
| SCHEMBL28394690 | 0.73 | ACHE (0.47) | ACHEMEN1KMT2AAPOBEC3GKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2573862-A1 | PHOTOELECTRIC CONVERSION ELEMENT USING THERMOSETTING SEALING AGENT FOR PHOTOELECTRIC CONVERSION ELEMENT | Nippon Kayaku Kabushiki Kaisha (JP) | 2013-03-27 | — | — | EP | disclosed |
| US-20130061925-A1 | Photoelectric Conversion Element Using Thermosetting Sealing Agent For Photoelectric Conversion Element | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2013-03-14 | — | — | US | disclosed |