Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20154933 | 0.79 | TSHR (0.40) | TSHRRORC | |
| SCHEMBL22426458 | 0.76 | TSHR (0.38) | TSHRRORC | |
| SCHEMBL23332701 | 0.76 | TSHR (0.38) | TSHRRORC | |
| SCHEMBL9968893 | 0.75 | — | — | |
| SCHEMBL20690894 | 0.74 | FFAR1 (0.37) | — | |
| SCHEMBL22435596 | 0.72 | TSHR (0.35) | TSHRRORC | |
| SCHEMBL22426583 | 0.72 | TSHR (0.35) | TSHRRORC | |
| SCHEMBL27310316 | 0.72 | RORC (0.37) | TSHRRORC | |
| SCHEMBL15854173 | 0.71 | — | — | |
| SCHEMBL17215396 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394829-B2 | Bi-functional quinoline analogs | GILEAD SCIENCES, INC. (US) | 2013-03-12 | — | — | US | disclosed |