Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766742 | 1.00 | GABRA1 (0.35) | GABRA1GABRB2CTSLCTSSCTSK | |
| SCHEMBL14765942 | 0.92 | GABRA1 (0.36) | GABRA1GABRB2FFAR4 | |
| SCHEMBL14766821 | 0.92 | GABRA1 (0.36) | GABRA1GABRB2FFAR4 | |
| SCHEMBL12735319 | 0.91 | FFAR4 (0.33) | GABRA1GABRB2CTSLCTSSCTSK | |
| SCHEMBL12739969 | 0.91 | FFAR4 (0.33) | GABRA1GABRB2CTSLCTSSCTSK | |
| SCHEMBL14766071 | 0.91 | FFAR4 (0.35) | GABRA1GABRB2FFAR4 | |
| SCHEMBL14766576 | 0.91 | FFAR4 (0.35) | GABRA1GABRB2FFAR4 | |
| SCHEMBL14767031 | 0.89 | GABRA1 (0.35) | GABRA1GABRB2FFAR4LMNAMEN1 | |
| SCHEMBL14767171 | 0.89 | GABRA1 (0.35) | GABRA1GABRB2LMNAMEN1ALDH1A1 | |
| SCHEMBL14766075 | 0.89 | GABRA1 (0.35) | GABRA1GABRB2LMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |