Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.41 |
| ▸ | NAAA | Q02083 | 3/20 | 0.37 |
| ▸ | RARB | P10826 | 3/20 | 0.35 |
| ▸ | RARA | P10276 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766410 | 0.97 | NAAA (0.40) | S1PR1NAAARARBRARAFFAR4 | |
| SCHEMBL14765849 | 0.97 | S1PR1 (0.40) | S1PR1NAAARARBRARAFFAR4 | |
| SCHEMBL14766107 | 0.94 | S1PR1 (0.37) | S1PR1NAAARARBRARAFFAR4 | |
| SCHEMBL14765943 | 0.93 | S1PR1 (0.37) | S1PR1NAAARARBRARAFFAR4 | |
| SCHEMBL12735389 | 0.91 | S1PR1 (0.42) | S1PR1NAAARARBRARAFFAR4 | |
| SCHEMBL14765737 | 0.91 | NAAA (0.43) | S1PR1NAAAFFAR4HRH3FFAR1 | |
| SCHEMBL14766399 | 0.88 | NAAA (0.39) | S1PR1NAAARARBRARAFFAR4 | |
| SCHEMBL14766007 | 0.88 | FFAR4 (0.36) | S1PR1FFAR4GABRA1GABRB2CNR2 | |
| SCHEMBL14766894 | 0.88 | FFAR4 (0.36) | S1PR1FFAR4GABRA1GABRB2CNR2 | |
| SCHEMBL12735391 | 0.88 | S1PR1 (0.40) | S1PR1NAAARARBRARAFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |