Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.35 |
| ▸ | PTGES | O14684 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14766252 | 0.97 | S1PR1 (0.42) | S1PR1S1PR3CNR2FFAR1FFAR4 | |
| SCHEMBL14766182 | 0.95 | FFAR1 (0.40) | S1PR1S1PR3CNR2FFAR1FFAR4 | |
| SCHEMBL14766860 | 0.94 | CNR2 (0.40) | S1PR1S1PR3CNR2FFAR1FFAR4 | |
| SCHEMBL14767181 | 0.93 | CNR2 (0.42) | CNR2CNR1PTPN11PSEN1PTGES | |
| SCHEMBL14765970 | 0.93 | CNR2 (0.42) | CNR2CNR1PTPN11PSEN1PTGES | |
| SCHEMBL14766654 | 0.92 | CNR2 (0.40) | S1PR1S1PR3CNR2FFAR1FFAR4 | |
| SCHEMBL14766382 | 0.92 | S1PR1 (0.46) | S1PR1S1PR3FFAR1FFAR4PTPN11 | |
| SCHEMBL12736576 | 0.91 | FFAR4 (0.39) | S1PR1S1PR3FFAR1FFAR4PPARD | |
| SCHEMBL14766912 | 0.91 | CNR2 (0.42) | S1PR1S1PR3CNR2FFAR1CNR1 | |
| SCHEMBL14766147 | 0.90 | CNR2 (0.40) | S1PR1S1PR3CNR2FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |