SCHEMBL14766912

SCHEMBL14766912

C=CCCOc1ccc(OCc2ccc(-c3ccc(-c4ccc(OCCCC)cc4)c(F)c3F)cc2)cc1F

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.42
FFAR1 O14842 9/20 0.40
PPARD Q03181 6/20 0.40
CNR1 P21554 1/20 0.39
S1PR1 P21453 3/20 0.38
S1PR3 Q99500 2/20 0.38
FAAH O00519 1/20 0.37
PSEN1 P49768 2/20 0.36
PTPN11 Q06124 1/20 0.36
PTGES O14684 1/20 0.36
ALOX5 P09917 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14766860 0.97 CNR2 (0.40) CNR2FFAR1PPARDCNR1S1PR1
SCHEMBL14767298 0.96 CNR2 (0.42) CNR2FFAR1PPARDCNR1S1PR1
SCHEMBL14766942 0.95 CNR2 (0.43) CNR2FFAR1PPARDCNR1S1PR1
SCHEMBL14766654 0.93 CNR2 (0.40) CNR2FFAR1PPARDCNR1S1PR1
SCHEMBL14767082 0.93 FFAR1 (0.46) CNR2FFAR1PPARDPTGES
SCHEMBL14766750 0.92 FFAR1 (0.45) FFAR1PPARDS1PR1S1PR3FAAH
SCHEMBL14766147 0.91 CNR2 (0.40) CNR2FFAR1PPARDCNR1S1PR1
SCHEMBL14765797 0.91 S1PR1 (0.41) CNR2FFAR1PPARDCNR1S1PR1
SCHEMBL14767238 0.91 FFAR1 (0.44) CNR2FFAR1PPARDPTGES
SCHEMBL14767000 0.91 CNR2 (0.43) CNR2FFAR1PPARDCNR1S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed